Drug Uses

Zithromax is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, skin infections, ear infections, and sexually transmitted diseases.

How Taken

Zithromax comes as a capsule, tablet, and liquid to take it orally. It is usually taken once a day for 2-5 days. Take Zithromax exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well before each use to mix the medication evenly. The capsules and tablets should be taken with a full glass of water. Continue to take Zithromax even if you feel well. Do not stop taking Zithromax without talking to your doctor. Take Zithromax liquid at least 1 hour before or 2 hours after meals. The capsule and tablet may be taken with or without food. If it upsets your stomach, take it with food.

Warnings/Precautions

Before taking Zithromax, tell your doctor if you have liver disease. You may not be able to take Zithromax, or you may require a lower dose or special monitoring during treatment. Zithromax is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Zithromax passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

Possible Side Effects

If you experience any of the following serious side effects, stop taking Zithromax and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue). Other, less serious side effects may be more likely to occur. Continue to take Zithromax and talk to your doctor if you experience nausea, vomiting, diarrhea, or abdominal pain; unusual dizziness, fatigue, or headache; vaginal yeast infection; a rash; or increased sensitivity to sunlight. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Zithromax tablets should be stored between 15° to 30° C (59° to 86°F). Store constituted suspension between 5° to 30°C (41° to 86°F) and discard when full dosing is completed or within 10 days. Shake well before each use. Oversized bottle provides shake space. Keep tightly closed.

Overdose

Seek emergency medical attention. Symptoms of Zithromax overdose include nausea, vomiting, diarrhea, and abdominal discomfort.

More Information

Avoid prolonged exposure to sunlight. Zithromax may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Scientists have confirmed their suspicions that a strain of hospital bacteria Staphylococcus aureus acquired resistance to the powerful drug vancomycin from another species of bacteria also commonly found in hospitals.
The two bacteria were present in the wound of a patient in a Michigan hospital in June 2002.
The confirmation came when researchers sequenced DNA from S. aureus and concluded that the DNA, which carried genes for vancomycin resistance, had almost certainly come from the bacterium Enterococcus faecalis. Apparently the resistance genes had “jumped” from one microbe to another.
Scientists have known that in the laboratory the two species can exchange genes for resistance to vancomycin. But the new study marks the first time scientists have documented how the exchange occurred in real life.
Scientists at the Centers for Disease Control and Prevention in Atlanta, Georgia, led the research. The findings appear in Science.
“The really important observation is that this [exchange] happened in a clinical environment,” says Steven R. Gill of The Institute for Genomic Research (TIGR) in Rockville, Maryland, where the DNA was sequenced.
S. aureus is already resistant to most antibiotics, and scientists had long-anticipated that the bacterium would become resistant to vancomycin, leaving physicians without a last-resort treatment.
More than a year ago, doctors’ fears came true when they discovered S. aureus resistant to vancomycin in a Michigan dialysis patient. Staph bacteria can still be treated with some antibiotics.
Bacterial genomes have large amounts of DNA that can move around on chromosomes, between organisms, and even jump between species. This enables them to pass traits such as drug resistance from one to another.
Antibiotic resistance is a growing health concern, which led the U.S. Department of Health and Human Services to launch a campaign in September called “Get Smart: Know When Antibiotics Work” to alert doctors and patients to be cautious in using antibiotics.

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