Drug Uses

Wellbutrin SR (Anti Depressant) is a pharmaceutical prescription antidepressant, which acts directly on the brain and other nerve cells. It is also used to treat ADHD (Attention Deficit Disorder), bipolar depression, chronic fatigue syndrome, cocaine addiction, nicotine addiction, and lower back pain. Also, aids in quitting smoking (identical to Zyban). It is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents.

How Taken

Wellbutrin SR comes as a tablet to take it orally. It is usually taken one to three times a day and may be taken with or without food. Do not crush, chew, or divide Wellbutrin SR. Do not stop taking Wellbutrin SR without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will want to decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

Warnings/Precautions

Before taking Wellbutrin SR, tell your doctor if you have: history of seizures or head injury or brain tumor, heart disease, liver or kidney disease, eating disorder, diabetes, alcohol dependence, any allergies, the intent to quit smoking. Because of the possibility this drug will make you dizzy and affect coordination, do not drive or operate machinery until you get used to the drug's effects. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking Wellbutrin SR may increase the risk of having seizures. Suddenly stopping certain tranquilizers is not recommended because doing so may increase the risk of having seizures. If you are over 65 years old you may be more sensitive to the effects of this drug. Tell your doctor if you are pregnant or plan to become pregnant before taking this drug. This drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Missed Dose

Take any missed dose as soon as possible but not if it is within 4 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.

Possible Side Effects

This medication is generally well tolerated. Dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision may occur. If these effects persist or worsen, notify your doctor. Report promptly: unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely but report promptly: tremor, dizziness, fainting, mood changes, slowed movements, difficulty urinating, decreased sex drive, and drowsiness. Very unlikely but report promptly: seizures, mental problems, fever, muscle aches, yellowing of the eyes or skin. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms may include trouble breathing, rash, itching, swelling, or severe dizziness. If you notice other effects not listed above, contact your doctor or pharmacist.

Storage

Store at controlled room temperature, 20° to 25°C (68° to 77°F). Dispense in a tight, light-resistant container.

Overdose

Seek emergency medical attention if an overdose is suspected. Symptoms of a Wellbutrin SR overdose include seizures, hallucinations, loss of consciousness, weakness, a fast heartbeat, and heart attack.

More Information

Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. Too much of this medicine can increase the risk of a seizure. Limit the consumption of caffeine while taking Wellbutrin SR.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Hundreds of thousands of people with moderate depression or anxiety have been put on powerful anti-depressants unnecessarily, the country's most senior medical experts will warn tomorrow.
Serious concerns about the overprescription of antidepressants such as Seroxat and Prozac will be spelled out by the two bodies regulating the safety and use of medicines in Britain.
They will advise that for people with mild to moderate depression, or with moderate anxiety, they may be better off seeking other treatment such as therapy or even daily exercise.
After months reviewing the international data on the drugs, known as SSRIs (selective serotonin reuptake inhibitors), the government's drugs regulator, the Medicines and Healthcare Products Regulatory Agency, has concluded that GPs are prescribing far too many pills for people who do not have a serious clinical condition.
They will warn doctors they need to think 'long and hard' before putting patients on the medication.
At a press conference tomorrow, Professor Kent Woods, mental health tsar Louis Appleby, and the chief executive of the National Institute for clinical Excellence (Nice), Andrew Dillon, will give their reasons for the warning.
It is expected thousands of people who are on the medication may want to come off it following tomorrow's announcement, but the experts will warn it is vital that they initially contact their doctor to talk about it. Anyone coming off SSRIs quickly can go through acute and dangerous withdrawal symptoms and become suicidal and paranoid.
Professor Woods will out line the findings of the review alongside the publication of new Nice guidelines to the NHS on the treatment of depression and anxiety.
Seroxat, the best-selling anti-depressant in the UK, will be described tomorrow as not suitable for every patient who is suffering from mild to moderate anxiety. The move comes after The Observer revealed last month that its manufacturer, GlaxoSmithKline, was marketing it to doctors specifically as a treatment for 'social anxiety disorders'.
Every year in Britain, some 13 million prescriptions are written out for SSRIs, such as Prozac. The drugs have enjoyed popularity over the past decade because they are much safer, with fewer side effects than the older tricyclic drugs which could easily kill patients who overdosed.
But concerns about SSRIs have emerged in recent years. Last year the government banned their prescription to people under 18s and they have been linked to a spate of suicides in young people in both the UK and the US.
European health authorities have also warned that extra care should be taken in prescribing SSRIs to people under 30.
The drugs, which were designed specifically to counter depression, have also been subjected to intensive scrutiny by the current health select committee investigation into the influence of the pharmaceutical industry.
MPs on the committee have heard concerns from campaigners that the anti-depressants were prescribed too liberally, with the result that millions of people are taking them with little benefit. Introduced to the UK 15 years ago, anti-depressants have been prescribed for a raft of lesser mental conditions such as anxiety disorders and phobias.
Concerns about the pills' addictive nature have led to fears that patients find it difficult to come off them.
Professor David Healy, a psychopharmacologist at Cardiff University, who has given evidence to the health select committee, called for the drug licensing authorities to go much further than merely trying to restrict the supply of anti-depressants.
'The MHRA should concentrate on telling people a little bit more about the risk of them getting hooked on anti-depressants, rather than simply warning the drugs should not be prescribed to those who are anxious,' Healy said.
An internal memo from Prozac's manufacturer, GlaxoSmithKline, written in 1998, revealed that trials of the drug in children were no better than a placebo when it came to relieving depression.
'It would be commercially unacceptable to include a statement that the efficacy had not been demonstrated, as this would undermine the profile [of the drug],' the memo stated.

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