Drug Uses

Retin-A is often used to improve the appearance and texture of the skin. It produces a mild, superficial peel of the epidermis. Retin-A has effects on the both the superficial (epidermis) and the deep (dermis) parts of the skin. The major benefit is to decrease the effects of sunlight caused aging by increasing the speed with which the surface cells are replaced.

How Taken

Apply a thin layer to affected area once a day at bedtime. Use a gauze pad or cotton swab to apply the liquid. Wash your hands immediately after use. Using this medication more frequently or in excessive amounts does not improve the results, but may increase side effects. Avoid applying near the eyes, mouth, or open cuts since this medication can irritate sensitive skin. Acne may appear to worsen when the medication is first used; continue therapy. It may take three to six weeks before the full benefits of this medication are seen. Use mild soap when washing your face. Do not wash face excessively. Abrasive soaps, cleansers, medicated creams or lotions can increase skin irritation. Consult your doctor or pharmacist about their use. Use other acne preparations with caution while using this medication.

Warnings/Precautions

This medication can increase sensitivity to sunlight, wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. This medication should be used during pregnancy only if clearly needed. It is not known if Retin-A appears in breast milk. Consult your doctor before breast-feeding.

Missed Dose

If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Possible Side Effects

Due to the possibility of irritation, it is advisable to begin treatment on a small area of skin. Exposure to the sun or to ultraviolet rays causes additional irritation. During treatment, such exposure should be avoided as much as possible or a sun block should be used. During the first weeks of treatment there may be an apparent worsening of the problem. Such a reaction is perfectly normal because small cysts deep within the skin are being eliminated at an accelerated rate. This medication can increase sensitivity wind and cold. Avoid prolonged exposure to the sun and sunlamps. Wear protective clothing and use an effective sunscreen. If any ingredient should cause hypersensitivity, discontinue use.

Storage

Store at room temperature away from sunlight. Keep this and all medications out of the reach of children.

Overdose

Applying Retin-A excessively will not produce faster or better results, and marked redness, peeling, or discomfort could occur. Over dosage with other retinoid has been associated with transient headache, facial flushing, celosias, abdominal pain, dizziness and ataxia.

More Information

If you have been previously treated with keratolytic preparations or exfoliants, you should wait until any skin rash clears up before beginning even low strength treatment. Studies of the effect of this product on pregnant women are incomplete. For this reason, it should only be applied when absolutely necessary and always under a doctor's supervision. The effectiveness of Retin-A is almost always accompanied by skin irritation. In the treatment of acne, this phenomenon is directly related to the effectiveness of the product and disappears once applications are more spaced out. Cosmetics may be used, but clean skin thoroughly before applying the medication.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Two proteins may help fight skin cancer
CHAPEL HILL, N.C., March 19 (UPI) -- U.S. researchers have identified two proteins that might help the body protect itself against skin cancer.
The University of North Carolina at Chapel Hill School of Medicine study indicates the proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.
Ultraviolet radiation can damage skin cells and, if left unrepaired by the cell, it can cause cancerous mutations.
But before cells begin to divide, they must replicate their DNA to form new daughter cells. If damage in the DNA is discovered even after the cell has started to replicate its DNA, the Timeless/Tipin complex sends a signal that slows the replication. That slowdown, said the researchers, might give the cell additional time to repair its DNA and potentially save itself from becoming cancerous or from dying in response to ultraviolet radiation.

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