Drug Uses

Nasonex is a nasal allergy spray for the treatment of seasonal and perennial allergy symptoms. Nasonex helps relieve itchy, runny noses, sneezing and congestion caused by dust mites, pet dander and tree and grass pollen. Nasonex Nasal Spray is a corticosteroid demonstrating anti-inflammatory properties. The Corticosteroids have been shown to have a wide range of effects on multiple cell types.

How Taken

Shake Nasonex well before each use. Prime the spray pump as instructed by your pharmacist. Use as directed generally two sprays in each nostril daily. Do not use this drug more often or longer than prescribed. Use Nasonex regularly during the prescribed treatment period for full benefit. If the drug is used for seasonal allergy, therapy is best started 2-4 weeks before the season. Improvement in symptoms occurs generally within 2 days and full benefit occurs after 1-2 weeks of use.

Warnings/Precautions

Before using Nasonex, tell your doctor and pharmacist if you have a viral, bacterial, or fungal infection of any kind. The absorption of this drug into your system can inhibit your body's ability to fight off infections. You may not be able to use Nasonex if you have an infection. Before using Nasonex, tell your doctor if you have a nasal septum ulcer, recently had nasal surgery, or nasal damage. You may not be able to use Nasonex, or you may require a dosage adjustment or special monitoring during your treatment. Nasonex is in the FDA pregnancy category C. This means that it is not known whether Nasonex will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant. It is unknown whether Nasonex passes into breast milk. Do not use Nasonex without first talking to your doctor if you are breast feeding a baby. Nasonex is not approved for children use younger than 3 years of age.

Missed Dose

If you miss a dose of Nasonex, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Possible Side Effects

Headache or sore throat might occur. If these effects persist or worsen, notify your doctor promptly. Very unlikely but report promptly: vision changes, unusual nasal bleeding or irritation/pain, blood-tinged mucus/phlegm, unusual increase in thirst or urination, nausea, weakness, weight loss. In the unlikely event you have an allergic reaction to Nasonex, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Storage

Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F). Protect from light. When Nasonex Nasal Spray, 50 mcg is removed from its cardboard container, prolonged exposure of the product to direct light should be avoided. Brief exposure to light, as with normal use, is acceptable.

Overdose

An overdose of this medication is not likely to occur. If you do think that an overdose has occurred, call an emergency room or poison control left.

More Information

Avoid items or activities that you know are allergens for you if they make your symptoms worse. Clean areas where dust or pet fur may aggravate your condition. Avoid exposing yourself to known sources of infection. Stay away from people with chicken pox, measles, or any other type of infectious disease. Your immune system may not be strong enough to fight off an infection while you are using Nasonex.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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It's known that exposure to ozone is associated with increased cardiovascular and pulmonary hospitalizations and deaths, but the actual mechanisms involved haven't been clarified. This study, by Duke University Medical Center pulmonary researchers, may provide some answers.
They found that mice exposed to unhealthy ozone levels showed amplified lung injury in response to bacterial toxins. The rodents also showed increased "programmed cell death" of the type of innate immune system cells that normally devour foreign invaders and keep the airways clear.
The innate immune system -- the most primitive part of the body's defenses -- reacts indiscriminately to any invader.
"Small amounts of inhaled foreign material can be relatively harmless, since they stimulate an appropriate innate immune response that protects the lungs," study lead author and pulmonologist Dr. John Hollingsworth, said in a prepared statement.
"However, it appears that ozone causes the innate immune system to overreact, killing key immune cells, and possibly making the lung more susceptible to subsequent invaders, such as bacteria," he said.
The study is published in the Oct. 1 issue of the Journal of Immunology.

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