Drug Uses

Gris-PEG is prescribed for the treatment of the following ringworm infections: Athlete's foot, Barber's itch (inflammation of the facial hair follicles), Ringworm of the body, Ringworm of the groin and thigh, Ringworm of the nails, Ringworm of the scalp. Because Gris-PEG is effective only for certain types of fungal infections, before treatment your doctor may perform tests to identify the source of infection.

How Taken

Accurate diagnosis of the infecting organism is essential. Adults: Daily administration of 330 mg (as a single dose or in divided amounts) will give a satisfactory response. Children: Approximately 3.3 mg per pound of body weight per day is an effective dose for most children.

Warnings/Precautions

Because Gris-PEG can make you sensitive to light, avoid exposure to intense natural or artificial sunlight. Notify your doctor if you develop lupus erythematosus (a form of rheumatism) or a lupus-like condition. Signs and symptoms of lupus include arthritis, red butterfly rash over the nose and cheeks, tiredness, weakness, sensitivity to sunlight, and skin eruptions. If you are being treated with Gris-PEG for an extended period of time, your doctor should perform regular tests, including periodic monitoring of kidney function, liver function, and blood cell production. Gris-PEG has not been proved safe and effective for the prevention of fungal infections. Gris-PEG may decrease the effectiveness of birth-control pills. Use additional protection while you are taking Gris-PEG. Men should wait at least 6 months after finishing therapy with Gris-PEG before they father a child. Women should avoid becoming pregnant while they are taking the drug.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

Possible Side Effects

When adverse reactions occur, they are most commonly of the hypersensitivity type such as skin rashes, urticaria, erythema multiform-like drug reactions, and rarely, angioneurotic edema, and may necessitate withdrawal of therapy and appropriate countermeasures. Paresthesias of the hands and feet have been reported rarely after extended therapy. Other side effects reported occasionally are oral thrush, nausea, vomiting, epigastria distress, diarrhea, headache, fatigue, dizziness, insomnia, mental confusion, and impairment of performance of routine activities. Administration of the drug should be discontinued if granulocytopenia occur. When rare, serious reactions occur with Gris-PEG, they are usually associated with high dosages, long periods of therapy, or both.

Storage

Store Gris-PEG tablets at controlled room temperature 15°-30°C (59°-86°F) in tight, light-resistant containers.

Overdose

Any medication taken in excess can have dangerous consequences. If you suspect an overdose of Gris-PEG, seek emergency medical treatment immediately.

More Information

Gris-PEG may intensify the effects of alcohol. If you drink alcohol while taking this medication, your heart may start beating faster and your skin may be flushed. If Gris-PEG is taken with certain other drugs, the effects could be increased, decreased, or altered. It is especially important to check with your doctor before combining Gris-PEG with the following: Blood-thinning drugs such as Coumadin, Barbiturates such as Phenobarbital, Oral Contraceptives.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Common bacterial infections of the skin
Our skin is host to a number of bacteria, most of which are beneficial. Including the friendly flora in our gut, more than 200 species of bacteria reside within the tissues exposed to the external environment. Skin infections result from these bacteria when the integrity of the skin breaks down or when the immune defense system is weak.
Skin infections can occur on the skin surface or deeper within the skin tissue. The most common bacteria that infect the skin are Staphylococcus aureus and Streptococcus pyogenes.
Types of bacterial infections
Impetigo and ecthyma
Impetigo begins with a redness of the skin and progresses to blisters that fill with fluid and itch, and then produce honey-coloured crusts. Lesions usually form around the nose and face. Ecthyma is a deeper version of impetigo that usually forms on the legs. It causes large boils, crusts, and deep sores that leave scars.
Folliculitis
Folliculitis is an infection of the hair follicles. It produces pimplelike skin bumps and small blisters with pus. Folliculitis occurs on the face, upper trunk, arms and buttocks. When the infection goes deeper, feels tender, and produces more pus, it is furunculosis. Carbuncles are furuncles that have fused.
Abscess
An abscess is a deep infection that looks like a closed blister or an open hole with pus. It is usually tender and becomes sore and painful as the infection progresses.
Erysipelas and cellulitis
Erysipelas is a superficial infection that tends to occur in young children and the elderly. It is also seen in those who have chronic swelling of the limbs, are addicted to alcohol, have diabetes mellitus, or have experienced trauma. Erysipelas mostly occurs on the face or legs. A fever occurs abruptly, the cheeks become red, and the skin feels hot, tense, and swollen. Cellulitis is a deeper form of this infection.

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