Drug Uses

Famvir is an oral antiviral prescription medication that is prescribed for: treatment of recurrent genital herpes in otherwise healthy patients; suppression of recurrent genital herpes in otherwise healthy patients; treatment of recurrent herpes simplex virus infections (genital herpes and cold sores) in HIV-infected patients and herpes zoster (shingles).

How Taken

Famvir can be prescribed in one of three ways:
-Episodic treatment: your doctor treats an outbreak of genital herpes as it occurs. The usual dose of Famvir is one 125-mg pill, twice a day, for 5 days.
-Suppressive treatment: if you have frequent or severe outbreaks, you take one 250-mg pill, twice a day, for up to 1 year to suppress the genital herpes virus and help to prevent outbreaks.
-Patients with HIV: Famvir is the only prescription oral antiviral therapy indicated for treating genital. In patients with herpes simplex and HIV, the dose of Famvir is 500 mg, twice a day, for 7 days.
Famvir can be taken with or without food.

Warnings/Precautions

Do not take Famvir if you are allergic to penciclovir (Denavir) without first talking to your doctor. Before taking this medication, tell your doctor if you have kidney disease. You may need a dosage adjustment or special monitoring during treatment with Famvir. Famvir (Pregnancy Category B) should be used during pregnancy only if the benefit to the patient clearly exceeds the risk to the fetus.

Missed Dose

IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Possible Side Effects

Stop taking Famvir and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to take Famvir and talk to your doctor if you experience nausea or vomiting, a headache, diarrhea, dizziness, tingling in your hands or feet, or itching.

Storage

Store between 15C and 30C (59F and 86F) and out of reach of children.

Overdose

Seek emergency medical attention. A Famvir overdose has no known symptoms, but an overdose of acyclovir (Zovirax), which is a similar drug, may cause seizures, hallucinations, and kidney damage (decreased urine production).

More Information

Treatment with Famvir should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters). Take all of the Famvir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Herpes infections are contagious and you can infect other people, even during treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission. For more information, talk to your doctor, pharmacist or health care provider.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Herpes infections down, but still are a concern
CHICAGO - Nearly 25 years after a news magazine declared that an epidemic of genital herpes threatened to undo the sexual revolution, a new study finds an encouraging decline in the percentage of people infected with the herpes virus.
Back in 1982, a Time cover story headlined “The New Scarlet Letter” sounded an alarm that seems mild now compared to concern over another sexually transmitted lifetime infection, the AIDS virus.
The new study shows a 19 percent drop since 1994 in the percentage of Americans ages 14 to 49 testing positive for herpes type 2, the most common cause of the recurring painful sores of genital herpes. The declines were especially pronounced among young people.
The findings, appearing in Wednesday’s Journal of the American Medical Association, represent biological evidence of a decrease in risky sexual behavior among adolescents, said lead author Dr. Fujie Xu of the Centers for Disease Control and Prevention.
“Overall, this is good news. There is a decrease occurring among all youth, males and females, and in all racial groups,” Xu said. “That’s very encouraging.”
But herpes is still uncomfortably common. Despite the decline, blood tests of more than 11,000 people found 11 percent of men and 23 percent of women carry the genital herpes, or type 2, virus. Among people in their 20s, the infection rate was almost 11 percent.
Ironically, the rates have dropped back to about where they were when Time ran its cover story, said study co-author Dr. Stuart Berman of the CDC.
“If it was a scarlet letter then, I don’t know what you call it now and there’s more HIV around,” Berman said. Herpes greatly increases the chances of infection with HIV, the virus that causes AIDS.
“It’s still an epidemic,” said Dr. Tom Cherpes of the University of Pittsburgh School of Medicine, who was not involved with the study. “The fact that there’s a trend downward should not be construed by anybody that herpes is under control.”
In addition, 56 percent of men and 60 percent of women tested positive for the oral herpes virus, type 1, which is best known as the culprit behind cold sores, but can spread to the genitals through oral sex. Type 1 may be causing more genital infections in some groups, such as college students, Xu and Berman said.
Herpes can be treated with antiviral drugs, which can help prevent flare-ups and reduce the risk of spreading it to others. Condoms can help lower the risk of transmission, although they’re not foolproof. Infected people are contagious even without symptoms.
The study was funded by the CDC. A previous CDC report in 1997 found a 30 percent increase in herpes infection since the late 1970s.
“This new data really reverses the trend,” said study co-author Francis Lee of Emory University.
Dr. Kenneth Fife of the Indiana University School of Medicine, who was not involved in the study, noted that rates of infection are still disproportionately high among women and blacks. The study found 42 percent of blacks tested positive for herpes type 2, a decline of only 4 percent since 1994.
“Maybe we’ve finally gotten through to the young people that they need to change their behavior,” Fife said. “We still see plenty of genital herpes. There are adolescents who are becoming infected.”

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