Drug Uses
Celexa is in a class of drugs called selective serotonin reuptake inhibitors. Celexa affects chemicals in the brain that may become unbalanced and cause depression.
Celexa is used to treat depression.
How Taken
Celexa comes as a tablet taken by mouth. It is usually taken once daily and may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Celexa exactly as directed. Do not take more or less of it or take it more often that prescribed by your doctor.
Continue to take Celexa even if you feel well. Do not stop taking Celexa without talking to your doctor. This drug must be taken regularly for a few weeks before its full effect is felt.
Warnings/Precautions
Before taking Celexa, tell your doctor if you have liver disease, have kidney disease, suffer from seizures, or suffer from mania or have suicidal thoughts.
You may not be able to take Celexa, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Do not take Celexa without first talking to your doctor if you have had an allergic reaction to this medication in the past.
Celexa is in the FDA pregnancy category C. This means that it is not known whether Celexa will be harmful to an unborn baby. Do not take Celexa without first talking to your doctor if you are pregnant or could become pregnant during treatment.
Celexa passes into breast milk and may affect a nursing infant. Do not take Celexa without first talking to your doctor if you are breast-feeding a baby.
Missed Dose
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
Possible Side Effects
The most common side effect with Celexa is sexual problems in male patients.
Some other possible side effects include:
-nausea
-dry mouth
-sleepiness
-increase in sweating
Storage
Celexa tablets should be stored in a dry place at room temperature between 15° and 30°C
Overdose
Symptoms most often accompanying Celexa overdose, alone or in combination with other drugs and/or alcohol, included dizziness, sweating, nausea, vomiting, tremor, somnolence, and sinus tachycardia. In more rare cases, observed symptoms included amnesia, confusion, coma, convulsions, hyperventilation, cyanosis, rhabdomyolysis, and ECG changes.
More Information
Use caution when driving, operating machinery, or performing other hazardous activities. Celexa may cause dizziness. If you experience dizziness, avoid these activities.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Celexa or affect your condition.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Dr. Peter Schlegel of the Cornell Medical Center in New York, along with a colleague, recently treated two men for infertility and found when both patients stopped taking their prescription antidepressant medications -- selective serotonin reuptake inhibitors (SSRIs) -- their sperm counts dramatically increased. Schlegel then observed that when both men re-started their antidepressants, their fertility problems returned.
One patient was taking citalopram -- sold as Cipramil -- and the other was on sertraline, sold as Lustral. The second patient switched to venlafaxtine -- Effexor -- and again his sperm count dropped to near zero. Schlegel believes that because SSRI drugs affect both sperm count and the ability of sperm to move, the antidepressants may be preventing sperm from reaching the semen.
"The patients had normal sperm counts and motility before medication," Schlegel said. "On the medication they have deterioration of both. The same patients going on and off medication had the same pattern. It shows a strong association."
The U.S. Food and Drug Administration required most SSRI drugs to carry the agency's strongest "black box" warning in 2004 for their association with increased risk of suicide. Other common side effects of the drugs include impotence and delayed ejaculation.
Allan Pacey, senior lecturer in andrology at the University of Sheffield, said, "There does seem to be a major correlation. Maybe this is an unknown side effect of these drugs that is only just coming to light."
Schlegel's study linking low sperm count to SSRI drug use noted that an additional dozen patients reported similar effects from the antidepressants. Because of the small number of patients involved, the study's implications need verification, Schlegel said. A clinical trial involving 30 male patients taking sertraline has begun to bolster Schlegel's findings.
The researchers warned that men taking SSRIs to treat mental disorders, who are concerned about low sperm counts, should not alter their drug use without consulting a qualified medical professional.
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