Drug Uses

Butalbital/APAP/Caffeine is a barbiturate sedative mixed with a non-aspirin pain medication (acetaminophen) and caffeine. This non-narcotic pain medication and relaxant is often prescribed for tension headaches caused by contractions of the muscles in the neck and shoulder area, and migraine.

How Taken

Butalbital/APAP/Caffeine comes as a capsule and tablet to take by mouth. The usual dosage is one to two tablets every 4-6 hours, but should be taken as directed by your physician. Total daily dosage should not exceed 6 tablets. Extended and repeated use of this product is not recommended because of the potential for physical dependence.

Warnings/Precautions

Butalbital/APAP/Caffeine may cause you to become drowsy or less alert; therefore, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended until you know your response to this drug. If you are being treated for severe depression or have a history of severe depression or drug abuse, consult with your doctor before taking Butalbital/APAP/Caffeine. Use this drug with caution if you are elderly or in a weakened condition, if you have liver or kidney problems, or if you have severe abdominal trouble. This medication contains acetaminophen (Tylenol), which is toxic to your liver and can be fatal when take above the recommended dosage. The total daily dose of acetaminophen should not exceed 4000mg (4g), or 2000mg (2g) if you are elderly or a chronic user of acetaminophen. Keep in mind that many over the counter products contain acetaminophen, and each tablet of this product contains 325mg. If you are pregnant or plan to become pregnant, inform your doctor immediately. Butalbital/APAP/Caffeine can affect a developing baby. It also appears in breast milk. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.

Missed Dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Butalbital/APAP/Caffeine. More common side effects may include: Abdominal pain, dizziness, drowsiness, intoxicated feeling, light-headedness, nausea, sedation, shortness of breath, vomiting. Less common or rare side effects may include: Agitation, allergic reactions, constipation, depression, difficulty swallowing, dry mouth, earache, exaggerated feeling of well-being, excessive sweating, excessive urination, excitement, fainting, fatigue, fever, flatulence, headache, heartburn, heavy eyelids, high energy, hot spells, itching, leg pain, mental confusion, muscle fatigue, numbness, rapid heartbeat, ringing in the ears, seizure, shaky feeling, skin redness and/or peeling, sluggishness, stuffy nose, tingling.

Storage

Store below 86 F (30 C); dispense in a tight container and out of reach of children.

Overdose

An overdose of Butalbital/APAP/Caffeine, or combining this medication with alcohol or other central nervous system depressant, may lead to unconsciousness or perhaps death. Butalbital/APAP/Caffeine overdose is indicated by severe drowsiness, confusion, extreme weakness, hallucination, shortness of breath, too slow or troubled breathing, slurred speech, lack of coordination, vomiting with blood, unusually slow heartbeat.

More Information

Do not take Butalbital/APAP/Caffeine if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days. Dangerous side effects could result. Butalbital/APAP/Caffeine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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What is the first thing you do when you sense an impending headache? Probably rush to your medicines cabinet and pop a painkiller without a second thought. Sometimes you may even be taking a pain relief product in advance or even daily, perhaps, in order to fend off recurrent headaches or because you are anticipating a stressful situation ahead.
Whatever the case, pause for a moment and analyze the pattern of your headaches. Do they seem to have become more frequent and more intense with time, requiring medication more often than before? If yes, then most lokely you are suffering from what are called rebound headaches, which are nothing but medication overuse headaches.
What happens is that when you start taking pain relief products indiscriminately, much more often than what the doctor prescribed or the label recommends, your body kind of adapts to the medication with the result that each successive time you need a higher dose to combat headaches. And if you don’t do that, the frequency and intensity of your headaches increases, so much so that headaches become a daily phenomenon. You may even wake up with a dull headache that continues throughout the day.
The effect is similar to what happens when at the slightest hint of a headache, you reach for your cup of coffee because coffee seems to cure your headache. You then become a more frequent coffee drinker, till one day, the situation reaches a point where, if you don’t get your coffee in time, you start getting a headache. With time, the frequency of the headaches increases and so does your requirement for coffee. And the whole vicious cycle continues. It is the caffeine in your coffee that is the culprit here.
Rebound headaches are usually accompanied by restlessness and irritability. Although any pain relief product can trigger rebound headaches, some are more likely to fuel them than others. Common over-the-counter medications that contribute to rebound headaches are aspirin, ibuprofen, acetaminophen, more so if they come in combination with caffeine. Prescription drugs containing the sedative butalbital, such as Fiorinal, Fioricet and Esgic, migraine medicines and opium-derived medications are also the culprits.
Most people don’t realize that over-the-counter pain relief products are meant to give quick relief from occasional headaches. They must not to be taken indiscriminately on a regular basis for recurrent headaches because medication overdosing can set off a vicious cycle of rebound headaches. And the only way to break this cycle is to withdraw the medication that is fuelling it. Period. But that is a task easier said than done and requires professional help.
Consult your doctor for further rebound headaches information and do seek medical help if you are having a headache more than thrice a week, are regularly on pain relief products and your headaches seem to be getting worse despite medication and rest. The doctor will recommend whether to stop the medication right away or to withdraw it gradually. Your headaches may become worse before they get better because of medication withdrawal symptoms, but if you cooperate with your doctor, you can successfully break the rebound cycle within a month or two.
Most importantly, preventing any kind of headache from occurring too often is the best solution. This requires a conscious effort on your part and can be achieved by identifying and avoiding things that trigger headaches for you. Alternative therapies like yoga and meditation teach you to relax and develop a positive attitude towards life. Also, making small lifestyle changes like getting sufficient sleep, eating meals in time, exercising regularly and quitting smoking can go a long way in preventing nagging headaches.

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