Drug Uses

Antivert is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Antivert is used to treat nausea, vomiting, and dizziness associated with motion sickness. Antivert may also be helpful in treating vertigo. This medicine may also be used for other purposes.

How Taken

Antivert comes as a regular and chewable tablet and a capsule. For motion sickness, Antivert should be taken 1 hour before you start to travel. Doses may be taken every 24 hours if needed. For dizziness caused by an ear condition, follow your doctor's directions. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Antivert exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. The chewable tablets may be chewed or swallowed whole.

Warnings/Precautions

This medicine may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. This medicine will add to the effect of other depressants or alcohol. Ask your pharmacist if you have questions about which medicines are depressants. It is unknown if this medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Missed Dose

Since Antivert is usually taken as needed, missing a dose is usually not a problem. If you are taking Antivert on a regular schedule and you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Possible Side Effects

Stop taking Antivert and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to take Antivert and talk to your doctor if you experience drowsiness or dizziness; a dry mouth (may be relieved by sugarless gum, ice chips, saliva substitutes, or other products if bothersome); blurred vision; nervousness; insomnia; or constipation. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Dispense in tight, light-resistant containers. Store at controlled room temperature 15°-30°C (59°-86° F).

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual excitability, drowsiness, hallucinations, very slow or shallow breathing, and seizures.

More Information

Antivert may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all prescription and over-the-counter medicines that you are taking, and do not take any medicine without first talking to your doctor. Antivert is contraindicated in individuals who have shown a previous hypersensitivity to it. For more information, talk to your doctor, pharmacist or health care provider.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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What is motion sickness?
Motion sickness is a very common disturbance of the inner ear that is caused by repeated motion such as from the swell of the sea, the movement of a car, the motion of a plane in turbulent air, etc. In the inner ear (which is also called the labyrinth), motion sickness affects the sense of balance and equilibrium and, hence, the sense of spatial orientation.
What causes motion sickness?
Motion is sensed by the brain through three different pathways of the nervous system that send signals coming from the inner ear (sensing motion, acceleration, and gravity), the eyes (vision), and the deeper tissues of the body surface (proprioceptors). When the body is moved intentionally, for example, when we walk, the input from all three pathways is coordinated by our brain. When there is unintentional movement of the body, as occurs during motion when driving in a car, the brain is not coordinating the input, and there is thought to be discoordination or conflict among the input from the three pathways. It is hypothesized that the conflict among the inputs is responsible for motion sickness.
For example, when we are sitting watching a picture that depicts a moving scene, our vision pathway is telling our brain that there is movement, but our inner ear is telling our brains that there is no movement. Thus, there is conflict in the brain, and some people will develop motion sickness in such a situation (even though there is no motion).
The cause of motion sickness is complex, however, and the role of conflicting input is only a hypothesis, or a proposed explanation, for its development. Without the motion–sensing organs of the inner ear, motion sickness does not occur, suggesting that the inner ear is critical for the development of motion sickness. Visual input seems to be of lesser importance, since blind people can develop motion sickness. Motion sickness is more likely to occur with complex types of movement, especially movement that is slow or involves two different directions (for example, vertical and horizontal) at the same time.
The conflicting input within the brain appears to involve levels of the neurotransmitters (substances that mediate transmission of signals within the brain and nervous system) histamine, acetylcholine, and norepinephrine. Many of the drugs that are used to treat motion sickness act by influencing or normalizing the levels of these compounds within the brain.
What are the symptoms of motion sickness?
The symptoms of motion sickness include nausea, vomiting, and dizziness (vertigo). Other common signs are sweating and a general feeling of discomfort and not feeling well (malaise).
Is there a difference between motion sickness and sea sickness?
There is no difference between motion sickness and sea sickness. Some people experience nausea and even vomiting when riding in an airplane, automobile, or amusement park ride. This condition is generally called motion sickness. Many people experience motion sickness when riding on a boat or ship. This is commonly referred to as sea sickness (mal de mer), even though it is the same disorder. They are one and the same phenomenon and will subsequently be referred to as motion sickness.
How does our sense of balance work?
Motion sickness relates to our sense of balance and equilibrium. Researchers in space and aeronautical medicine call this sense spatial orientation, because it tells the brain where the body is "in space:" what direction it is pointing, what direction it is moving, and if it is turning or standing still.
Our sense of balance is regulated by a complex interaction of the following parts of the nervous system:
1. The inner ears (also called the labyrinth) monitor the directions of motion, such as turning or forward–backward, side–to–side, and up–and– down motions.
2. The eyes observe where the body is in space (for example, upside down, right side up, etc.) and also the directions of motion.
3. Skin pressure receptors such as those located in the feet and seat sense what part of the body is down and touching the ground.
4. Muscle and joint sensory receptors report what parts of the body are moving.
5. The central nervous system (the brain and spinal cord) processes all the bits of information from the four other systems to make some coordinated sense out of it all.

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